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Dymista Nasal Spray

from£29.99

Dymista Nasal Spray is a prescription medication used to treat symptoms of allergic rhinitis, such as nasal congestion, sneezing, and a runny or itchy nose. It combines two active ingredients: azelastine hydrochloride, an antihistamine that reduces allergy symptoms, and fluticasone propionate, a corticosteroid that reduces inflammation in the nasal passages. This dual-action formula provides fast and effective relief from both seasonal and year-round allergies. Dymista is suitable for use in adults and children aged 6 years and older and is typically used twice daily.

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Hayfever and allergies

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Nasal spray

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Dymista Nasal Spray
SKU: DYMISTSPR Category: Tags: ,

Additional information

Quantity

1 x 120 dose spray, 2 x 120 dose spray, 3 x 120 dose spray, 4 x 120 dose spray

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Independent prescriber, Superintendent pharmacist.


Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

Medical coaching


What is Dymista nasal spray?

Dymista Nasal Spray contains two key active ingredients: azelastine hydrochloride and fluticasone propionate, which work together to provide effective relief from the symptoms of allergic rhinitis.

  • Azelastine hydrochloride is an antihistamine, a type of medication that blocks the effects of histamine—a chemical released by the body during an allergic reaction. By inhibiting histamine, azelastine helps to reduce symptoms such as itching, sneezing, and a runny nose associated with allergic rhinitis.
  • Fluticasone propionate is a corticosteroid, a class of medications known for their powerful anti-inflammatory properties. Corticosteroids like fluticasone work by reducing inflammation in the nasal passages, which helps to alleviate congestion, swelling, and irritation that occur as part of an allergic response.

Together, these two active ingredients in Dymista provide a comprehensive approach to managing both the immediate allergic reactions and the underlying inflammation, making it a highly effective treatment for both seasonal and perennial allergic rhinitis.

What are the active ingredients in Dymista nasal spray?

The active ingredients in Dymista nasal spray are: 137 micrograms of azelastine hydrochloride (an antihistamine) and 50 micrograms of fluticasone propionate (a steroid).

What is Dymista nasal spray used for?

Dymista Nasal Spray is used to alleviate the symptoms of moderate to severe seasonal and perennial allergic rhinitis when treatment with either an intranasal antihistamine or corticosteroid alone is insufficient. Seasonal and perennial allergic rhinitis are allergic reactions triggered by substances such as pollen (hay fever), dust mites, mold, or pet dander. Dymista Nasal Spray helps relieve allergy symptoms, including a runny nose, postnasal drip, sneezing, and an itchy or blocked nose.

How does Dymista nasal spray work?

Dymista Nasal Spray works by combining two active ingredients—azelastine hydrochloride and fluticasone propionate—that address both the allergic reaction and the inflammation associated with allergic rhinitis.
  • Azelastine hydrochloride is an antihistamine that blocks the action of histamine, a chemical released by the body during an allergic reaction. By preventing histamine from binding to its receptors, azelastine reduces symptoms like sneezing, itching, and a runny nose.
  • Fluticasone propionate is a corticosteroid that has strong anti-inflammatory properties. It works by reducing inflammation in the nasal passages, which helps to relieve nasal congestion, swelling, and irritation.
By targeting both the allergic response and the resulting inflammation, Dymista Nasal Spray provides comprehensive relief from the symptoms of allergic rhinitis, including a runny nose, postnasal drip, sneezing, and nasal congestion. This dual-action approach makes Dymista particularly effective for individuals whose symptoms are not adequately controlled by either an antihistamine or a corticosteroid alone.

How do you use Dymista nasal spray?

Always use Dymista Nasal Spray exactly as your doctor has instructed. If you are unsure about how to use it, consult your doctor or pharmacist. It's important to use Dymista Nasal Spray regularly to achieve the full therapeutic benefit. Avoid contact with the eyes.

Dosage:

  • Adults and adolescents (12 years and older): The recommended dose is one spray into each nostril in the morning and evening.
  • Children under 12 years: This medicine is not recommended for children under 12 years.

Use in Renal and Hepatic Impairment:

There is no available data for patients with renal or hepatic impairment.

Method of Administration:

Dymista Nasal Spray is intended for nasal use only. Follow the instructions carefully and use as directed.

Preparing the Spray:

  1. Shake the bottle gently for 5 seconds by tilting it up and down, then remove the protective cap.
  2. Prime the pump before the first use by pressing down and releasing it 6 times until a fine mist appears.
  3. If the spray has not been used for more than 7 days, re-prime the pump by pressing down and releasing it once.

Using the Spray:

  1. Shake the bottle gently for 5 seconds and remove the protective cap.
  2. Clear your nostrils by blowing your nose.
  3. Keep your head tilted slightly forward. Do not tilt your head backward.
  4. Hold the bottle upright and carefully insert the spray tip into one nostril.
  5. Close the other nostril with your finger, press down once on the pump, and sniff gently at the same time.
  6. Breathe out through your mouth and repeat the process in the other nostril.
  7. After each use, wipe the spray tip with a clean tissue or cloth and replace the protective cap.
  8. Do not attempt to clear a blocked nozzle by pricking it. Clean the actuator with water if needed.

Important Information:

  • Follow your doctor’s instructions regarding the dosage and duration of use.
  • Dymista Nasal Spray is suitable for long-term use, with the duration of treatment matching the period of allergy symptoms.

If You Use More Dymista Nasal Spray Than Recommended:

  • If you accidentally use too much, you are unlikely to experience serious problems. However, if you have concerns or have used higher-than-recommended doses for an extended period, contact your doctor.
  • If someone, particularly a child, accidentally ingests Dymista Nasal Spray, contact your doctor or visit the nearest hospital emergency department immediately.

If You Forget to Use Dymista Nasal Spray:

  • Use the spray as soon as you remember, then take the next dose at the usual time. Do not take a double dose to make up for a missed one.

If You Stop Using Dymista Nasal Spray:

  • Do not stop using Dymista Nasal Spray without consulting your doctor, as it may affect the success of your treatment.
If you have any further questions about using this medicine, ask your doctor or pharmacist.

Who should not use Dymista nasal spray?

Do Not Use Dymista Nasal Spray If:

  • You are allergic to azelastine hydrochloride, fluticasone propionate, or any other ingredients in this medication, please refer to the patient information leaflet.

Warnings and Precautions:

Consult your doctor or pharmacist before using Dymista Nasal Spray if:
  • You have recently had surgery on your nose.
  • You have an infection in your nose. Nasal infections should be treated with appropriate antibacterial or antifungal medication. You can continue using Dymista Nasal Spray to treat your allergies while receiving treatment for the infection.
  • You have tuberculosis or an untreated infection.
  • You have vision changes or a history of increased eye pressure, glaucoma, and/or cataracts. If this applies to you, you will be closely monitored while using Dymista Nasal Spray.
  • You have impaired adrenal function. Special care is needed when transitioning from systemic steroid treatment to Dymista Nasal Spray.
  • You have severe liver disease, which increases the risk of systemic side effects.
In these situations, your doctor will determine whether Dymista Nasal Spray is appropriate for you. It's important to follow the dosing instructions in the patient information leaflet or as advised by your doctor. Using higher-than-recommended doses of nasal corticosteroids may lead to adrenal suppression, which can cause symptoms like weight loss, fatigue, muscle weakness, low blood sugar, salt cravings, joint pain, depression, and darkened skin. Your doctor may recommend additional medication during periods of stress or surgery. To avoid adrenal suppression, your doctor will prescribe the lowest effective dose to control your rhinitis symptoms. Long-term use of nasal corticosteroids like Dymista may slow growth in children and adolescents. Your child's height will be regularly monitored, and your doctor will ensure they are taking the lowest possible effective dose. Contact your doctor if you experience blurred vision or other visual disturbances. If you are unsure whether any of these conditions apply to you, talk to your doctor or pharmacist before using Dymista Nasal Spray.

Children:

This medicine is not recommended for children under 12 years.

Pregnancy and Breastfeeding:

If you are pregnant, breastfeeding, think you may be pregnant, or are planning to have a baby, consult your doctor or pharmacist before using Dymista Nasal Spray.

Driving and Using Machines:

Dymista Nasal Spray may have a minor effect on your ability to drive and use machinery. Very rarely, you may experience fatigue or dizziness due to your condition or while using Dymista Nasal Spray. If this happens, avoid driving or operating machinery. Be aware that consuming alcohol may enhance these effects.

Dymista Nasal Spray Contains Benzalkonium Chloride:

Each spray contains 14 micrograms of benzalkonium chloride, which may cause irritation or swelling inside the nose, especially with long-term use. If you experience discomfort while using the spray, inform your doctor or pharmacist.

What are the side effects with Dymista nasal spray?

Like all medications, Dymista Nasal Spray can cause side effects, although not everyone experiences them.

Very Common Side Effects (affecting more than 1 in 10 people):

  • Nosebleeds

Common Side Effects (affecting up to 1 in 10 people):

  • Headache
  • A bitter taste in your mouth, especially if you tilt your head back while using the nasal spray. This can be alleviated by drinking a soft drink a few minutes after using the spray.
  • Unpleasant smell

Uncommon Side Effects (affecting up to 1 in 100 people):

  • Slight irritation inside the nose, which may cause mild stinging, itching, or sneezing
  • Nasal dryness, cough, dry throat, or throat irritation

Rare Side Effects (affecting up to 1 in 1,000 people):

  • Dry mouth

Very Rare Side Effects (affecting up to 1 in 10,000 people):

  • Dizziness or drowsiness
  • Cataracts, glaucoma, or increased pressure in the eye, which may result in loss of vision and/or red, painful eyes. These effects have been reported after prolonged use of fluticasone propionate nasal sprays.
  • Damage to the skin and mucous membrane inside the nose
  • Feeling nauseous, weary, exhausted, or weak
  • Rash, itchy skin, or red, raised itchy bumps
  • Bronchospasm (narrowing of the airways in the lungs)

Seek Immediate Medical Help If You Experience:

  • Swelling of the face, lips, tongue, or throat, which may cause difficulty swallowing or breathing, and the sudden onset of a skin rash. These could be signs of a severe allergic reaction, though this is very rare.

Side Effects with Unknown Frequency (frequency cannot be estimated from available data):

  • Blurred vision
  • Sores in the nose
Systemic side effects (affecting the whole body) may occur if this medication is used at high doses for a long time. These effects are much less likely with corticosteroid nasal sprays than with oral corticosteroids, but they can still vary depending on the individual and the specific corticosteroid used. Nasal corticosteroids can affect normal hormone production in your body, especially if used in high doses for an extended period. In children and adolescents, this can lead to slower growth. In rare cases, long-term use of nasal corticosteroids has been associated with reduced bone density (osteoporosis).

Reporting Side Effects:

If you experience any side effects, including those not listed in this leaflet, talk to your doctor or pharmacist. You can also report side effects directly through the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or by searching for "MHRA Yellow Card" in the Google Play or Apple App Store. Reporting side effects helps provide more information on the safety of this medicine.

Does Dymista nasal spray interact with other medicines?

Inform your doctor or pharmacist if you are taking, have recently taken, or may take any other medications, including those obtained without a prescription. Certain medicines may enhance the effects of Dymista Nasal Spray, and your doctor may want to monitor you closely if you are using these medications (including some HIV treatments like ritonavir or cobicistat, and antifungal treatments like ketoconazole).

Dymista nasal spray FAQs

What is Dymista Nasal Spray?

Dymista is a prescription nasal spray that provides relief from the symptoms of allergic rhinitis, commonly known as hay fever. It combines two active ingredients: azelastine hydrochloride, an antihistamine, and fluticasone propionate, a corticosteroid. Together, these ingredients help to reduce inflammation and block allergic reactions triggered by dust, pollen, and other allergens. Dymista is manufactured by Mylan and comes in a convenient bottle containing approximately 120 metered sprays. It is suitable for use by adults and children over the age of 12.

Is Dymista Nasal Spray a steroid?

Yes, one of the active ingredients in Dymista is a steroid called fluticasone propionate. This steroid works by reducing inflammation in the nasal passages, which helps to relieve the symptoms of hay fever. The effectiveness of the steroid builds up with regular use, making it more effective at preventing nasal irritation over time.

What is Dymista used for?

Dymista is primarily used to treat hay fever, but it is also effective for year-round allergies, such as those caused by pets and house dust mites. The symptoms of allergic rhinitis that Dymista helps to alleviate include sneezing, congestion, itching, a runny nose, and itchy, red eyes.

How does Dymista work?

Dymista works by combining a corticosteroid and an antihistamine to provide a powerful, dual-action defense against allergy symptoms. Azelastine, the antihistamine, acts quickly to reduce symptoms like itching, sneezing, and a runny nose. Fluticasone propionate, the corticosteroid, targets inflammation, helping to reduce swelling in the nasal passages and relieve congestion.

How long does Dymista stay in your system?

Dymista can start working within 30 minutes of use, but it may take a few days to feel its full benefits. The effects typically last between 12 and 48 hours after use. For best results, it’s recommended to start using Dymista a few days before exposure to known allergens.

What are the alternatives to Dymista Nasal Spray?

Dymista is a prescription-only medication, but there are several over-the-counter (OTC) alternatives you can try first. These include antihistamine tablets like Piriton, Loratadine, and Cetirizine, as well as OTC steroidal nasal sprays like Pirinase and Beclometasone. Prescription alternatives include nasal sprays such as Avamys, Flixonase, Rhinolast, and Nasonex, and eye drop solutions like Opticrom and Optilast. Non-medicinal methods, such as wearing wraparound sunglasses, keeping windows closed, and showering regularly to remove pollen, can also help reduce hay fever symptoms.

What is the recommended dosage for Dymista?

For adults and children over 12 years old, the recommended dosage is one spray in each nostril, morning and evening. You should not exceed this dosage. While using more than the recommended amount is unlikely to cause serious problems, it may increase the likelihood of side effects.

What are the ingredients in Dymista Nasal Spray?

Dymista contains 137 micrograms of azelastine hydrochloride (an antihistamine) and 50 micrograms of fluticasone propionate (a steroid) per spray. Other inactive ingredients include disodium edetate, glycerol, microcrystalline cellulose, carmellose sodium, polysorbate 80, benzalkonium chloride, phenylethyl alcohol, and purified water.

What are the possible side effects of Dymista?

The most common side effects of Dymista include nosebleeds, headaches, and a bitter or unpleasant taste or smell, which can often be relieved by eating or drinking something after using the spray. Uncommon side effects include mild irritation or dryness in the nose or throat. If you experience any side effects not listed here, stop using Dymista and consult your doctor immediately.

What should I tell my doctor before using Dymista?

Before using Dymista, inform your doctor if you have had a nose operation, untreated infections (especially in the nose), tuberculosis, liver disease, glaucoma, cataracts, or impaired adrenal function. Also, tell your doctor if you are taking HIV medications like ritonavir or antifungal medications like ketoconazole. Do not use other nasal steroidal medicines simultaneously with Dymista. Make sure to read the Patient Information Leaflet thoroughly before using Dymista Nasal Spray.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.9450.pdf

Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

Medical coaching


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Independent prescriber, Superintendent pharmacist.


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