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Fibromyalgia

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What you should know about fibromyalgia

Fibromyalgia is a chronic condition characterized by widespread pain, fatigue, and tenderness in the muscles, joints, and other soft tissues. It often includes additional symptoms like sleep disturbances, headaches, and cognitive difficulties, commonly known as “fibro fog.”

The exact cause of fibromyalgia is not fully understood, but it is believed to involve a combination of genetic, environmental, and psychological factors. Possible triggers include physical or emotional trauma, infections, and abnormalities in pain processing by the central nervous system.

The primary symptoms of fibromyalgia include widespread muscle pain, fatigue, sleep disturbances, headaches, and cognitive difficulties. Some people may also experience irritable bowel syndrome (IBS), depression, and anxiety.

Fibromyalgia is typically diagnosed based on a history of widespread pain lasting more than three months, along with other symptoms like fatigue and sleep disturbances. There is no specific test for fibromyalgia, so diagnosis often involves ruling out other conditions.

Low Dose Naltrexone (LDN) is a medication that, in low doses, has been found to help reduce pain and inflammation in people with fibromyalgia. LDN works by modulating the immune system and increasing the body’s production of endorphins, which are natural painkillers. Many patients report improvements in pain, sleep, and overall well-being with LDN.

Treatment for fibromyalgia often includes a combination of medications (such as pain relievers, antidepressants, and LDN), physical therapy, exercise, stress management techniques, and lifestyle changes. The goal is to manage symptoms and improve quality of life.

There is currently no cure for fibromyalgia, but with proper treatment and lifestyle changes, many people can manage their symptoms and lead fulfilling lives. Treatment focuses on reducing pain, improving sleep, and managing other symptoms.

If you experience persistent, widespread pain, fatigue, or other symptoms that interfere with your daily life, it’s important to consult a healthcare provider. Early diagnosis and treatment can help manage symptoms more effectively and improve your quality of life.

Additional information

What is fibromyalgia?

Fibromyalgia is a chronic condition characterized by widespread pain throughout the body, often accompanied by fatigue, sleep disturbances, and cognitive difficulties. This complex and often misunderstood disorder affects the way the brain processes pain signals, leading to heightened sensitivity and discomfort in muscles, ligaments, and tendons. While fibromyalgia is not life-threatening, it can significantly impact a person’s quality of life, making daily activities more challenging.

What causes fibromyalgia?

The exact cause of fibromyalgia remains unclear, but it’s believed to involve a combination of genetic, environmental, and psychological factors. Some potential triggers include:

  • Genetics: Fibromyalgia often runs in families, suggesting a genetic predisposition to the condition.
  • Infections: Certain infections or illnesses may trigger or exacerbate fibromyalgia symptoms.
  • Physical or emotional trauma: Events like surgery, car accidents, or significant psychological stress can initiate fibromyalgia in some individuals.
  • Central nervous system dysfunction: Fibromyalgia is associated with abnormalities in how the central nervous system processes pain signals, leading to an exaggerated response to stimuli.

What are the symptoms of fibromyalgia?

Fibromyalgia manifests in various symptoms that can vary in intensity and duration. The most common symptoms include:

  • Widespread pain: Persistent pain that affects multiple areas of the body, often described as a dull ache that lasts for at least three months.
  • Fatigue: Even after a full night’s sleep, individuals with fibromyalgia often wake up feeling tired and may experience disrupted sleep due to pain or other sleep disorders.
  • Cognitive difficulties: Often referred to as “fibro fog,” this includes issues with concentration, memory, and mental clarity.
  • Sleep disturbances: Difficulty falling or staying asleep or experiencing non-restorative sleep is common in fibromyalgia sufferers.
  • Headaches: Many individuals with fibromyalgia experience frequent tension headaches or migraines.
  • Irritable Bowel Syndrome (IBS): Digestive issues such as IBS often accompany fibromyalgia, causing bloating, cramping, and abdominal pain.
  • Depression and anxiety: The chronic nature of fibromyalgia can lead to mental health challenges, including depression and anxiety.

How to treat fibromyalgia

Managing fibromyalgia typically involves a combination of medications, lifestyle changes, and alternative therapies. One emerging treatment option for fibromyalgia is Low Dose Naltrexone (LDN).

Low Dose Naltrexone (LDN) for fibromyalgia

LDN is a medication traditionally used to treat opioid addiction in higher doses. However, in low doses, it has shown promise as a treatment for chronic pain conditions like fibromyalgia. LDN is believed to work by modulating the body’s immune response and reducing inflammation, which in turn may decrease the pain and fatigue associated with fibromyalgia. It also helps to normalize the release of endorphins, which are natural painkillers produced by the body.

LDN is usually taken orally in doses ranging from 1.5 to 4.5 mg per day. Many patients report improvements in pain levels, sleep quality, and overall well-being after starting LDN. However, as with any medication, it’s essential to consult with a UK registered prescriber to determine if LDN is suitable for you.

How to prevent fibromyalgia

While there is no known way to prevent fibromyalgia, you can manage symptoms and improve your quality of life by:

  • Staying physically active: Regular, low-impact exercise such as walking, swimming, or yoga can help reduce pain and improve function.
  • Maintaining a healthy diet: A balanced diet rich in fruits, vegetables, lean proteins, and whole grains supports overall health and can help manage symptoms.
  • Prioritizing sleep: Good sleep hygiene practices, like maintaining a regular sleep schedule and creating a relaxing bedtime routine, are crucial for managing fibromyalgia.
  • Stress management: Techniques such as mindfulness, meditation, or cognitive-behavioral therapy (CBT) can help reduce stress and alleviate symptoms.
  • Avoiding triggers: Identify and avoid specific triggers that exacerbate your symptoms, such as certain foods, environmental factors, or activities.

When to seek medical attention

If you experience persistent, widespread pain or fatigue that interferes with your daily life, seeking medical advice is essential. Early diagnosis and treatment can help manage symptoms more effectively. Additionally, if you are already diagnosed with fibromyalgia but find that your current treatment plan is not providing sufficient relief, consulting with a healthcare provider is crucial to adjust your treatment strategy.

Buy online from Medical Mojo

At Medical Mojo, we offer a range of fibromyalgia treatments approved by UK-registered prescribers. Whether you’re looking to explore the benefits of Low Dose Naltrexone (LDN) or need advice on managing your symptoms, our online pharmacy provides a convenient, discreet service tailored to your needs. Shop with confidence and get the support you need to manage your fibromyalgia symptoms effectively.

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Independent prescriber, Superintendent pharmacist.


Checked By
Dr Syira Ahsan

Medical coach.


August 20, 2024
August 20, 2026

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