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Low Dose Naltrexone 1mg capsules

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Low dose naltrexone 1mg capsules: Supporting immune balance and reducing inflammation

Low Dose Naltrexone (LDN) 1mg capsules are specially formulated to help regulate the immune system and reduce inflammation. These low-dose capsules are commonly used off-label to manage a variety of autoimmune disorders and chronic pain conditions.

Taken once daily, LDN 1mg offers potential benefits for conditions such as multiple sclerosis, fibromyalgia, and Crohn’s disease. By modulating the immune response, it aims to improve symptom control and enhance overall well-being.

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Low Dose Naltrexone 1mg capsules
SKU: LDN4.5CPS-2 Categories: , Tags: , ,

Description

Product information: low dose naltrexone 1mg capsules

Description:

Low Dose Naltrexone (LDN) 1mg capsules are a specially formulated, low-dose version of naltrexone, an opioid receptor antagonist. Unlike the standard 50mg dose used for treating opioid and alcohol dependence, LDN is taken in much smaller amounts to help regulate the immune system and alleviate symptoms associated with various chronic conditions.

Uses:

Low Dose Naltrexone 1mg capsules are commonly used off-label to manage a range of conditions, including:

  • Autoimmune diseases: Conditions like multiple sclerosis, lupus, and rheumatoid arthritis
  • Chronic pain disorders: Examples include fibromyalgia and complex regional pain syndrome (CRPS)
  • Inflammatory bowel diseases: Such as Crohn’s disease and ulcerative colitis
  • Cancer support: Used as an adjunct to traditional cancer treatments to modulate the immune system
  • Other inflammatory or immune dysfunction conditions: Helpful for chronic inflammation and immune-related disorders

How it works:

LDN works by temporarily blocking opioid receptors in the body. This action is believed to stimulate the production of endorphins—natural painkillers—and regulate the immune system. By boosting endorphins, LDN can reduce inflammation, alleviate pain, and enhance immune system balance.

Dosage:

The typical dose of LDN for many conditions starts at 1mg, taken once daily, often at bedtime to align with the body’s natural rhythms. Dosages may vary depending on individual needs and the condition being treated. Always follow the instructions provided by your healthcare provider.

Side effects:

Common side effects of LDN 1mg capsules may include:

  • Sleep disturbances, such as vivid dreams or insomnia
  • Digestive issues, including nausea or an upset stomach
  • Mild headaches

These side effects are usually temporary and tend to improve as the body adjusts to the medication. If symptoms persist or worsen, consult your healthcare provider.

Precautions:

  • LDN should not be used by individuals currently taking opioid medications, as it may block their effects and cause withdrawal symptoms.
  • Inform your healthcare provider about all medications or supplements you are taking to avoid potential interactions.
  • Pregnant or breastfeeding women should consult their doctor before starting LDN.

Storage:

Store LDN 1mg capsules in a cool, dry place, away from direct sunlight and moisture. Keep them out of reach of children.

Consultation:

Always consult a healthcare provider before starting or adjusting your dosage of Low Dose Naltrexone. This ensures the medication is suitable for your specific condition and health requirements.

Additional information

Quantity

1 x 30, 2 x 30, 3 x 30

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patient leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


What are low dose naltrexone (LDN) 1mg capsules?

Low Dose Naltrexone (LDN) 1mg capsules are a specially compounded, low-dose version of naltrexone. While standard naltrexone tablets are typically available in 50mg strengths and are used for treating opioid and alcohol dependence, LDN is formulated in much smaller doses, such as 1mg, to support different therapeutic uses.

At higher doses, naltrexone blocks opioid receptors to treat addiction. However, when taken in low doses (ranging from 0.5mg to 4.5mg), it is believed to modulate the immune system and reduce inflammation. This mechanism makes LDN a promising off-label option for managing various autoimmune and chronic pain conditions.

Why is LDN used?

LDN 1mg capsules are commonly used as an off-label treatment for conditions such as multiple sclerosis, fibromyalgia, Crohn’s disease, rheumatoid arthritis, and other autoimmune or inflammatory disorders. By regulating the immune response and reducing inflammation, LDN may help improve overall symptom management and quality of life.

How is LDN taken?

LDN 1mg capsules are typically taken once daily, often at bedtime. While this dose is not FDA-approved for these conditions, it is widely used in clinical practice as a complementary treatment. Always follow your healthcare provider’s guidance for dosage and timing.

What is the active ingredient in Low Dose Naltrexone (LDN) 1mg capsules?

The active ingredient in the low-dose naltrexone capsules is naltrexone hydrochloride 1mg.

What are low dose naltrexone (LDN) 1mg capsules used for?

Low Dose Naltrexone (LDN) 1mg capsules are an off-label treatment option for a variety of chronic and inflammatory conditions. They are commonly used for the following purposes:

  • Autoimmune diseases: LDN is frequently prescribed to help manage autoimmune conditions such as multiple sclerosis (MS), rheumatoid arthritis, lupus, and Hashimoto’s thyroiditis. By modulating the immune system and reducing inflammation, it can help alleviate symptoms and improve overall well-being.
  • Chronic pain disorders: Conditions like fibromyalgia and complex regional pain syndrome (CRPS) may benefit from LDN, as it helps reduce pain and improve quality of life.
  • Inflammatory bowel diseases: LDN has shown promise in managing Crohn’s disease and ulcerative colitis by reducing gut inflammation and supporting digestive health.
  • Cancer support: Some patients use LDN as an adjunctive therapy alongside traditional cancer treatments to enhance the immune system and potentially improve outcomes. However, further research is needed in this area.
  • Neurological disorders: Emerging evidence suggests LDN may slow disease progression and improve symptoms in conditions like Parkinson’s disease and Alzheimer’s disease, although more studies are required.
  • Irritable bowel syndrome (IBS): LDN can help reduce intestinal inflammation, alleviating symptoms such as abdominal pain and irregular bowel movements.

LDN 1mg capsules are generally well-tolerated, but it is essential to consult a healthcare provider to determine whether this treatment is suitable for your specific condition and health needs.

What are low dose naltrexone (LDN) 1mg capsules used for?

Low Dose Naltrexone (LDN) 1mg capsules are a versatile off-label treatment used to manage a wide range of chronic and inflammatory conditions. Below are some of the common uses for LDN 1mg capsules:

  • autoimmune diseases: LDN is often prescribed to help manage autoimmune conditions such as multiple sclerosis (MS), rheumatoid arthritis, lupus, and Hashimoto’s thyroiditis. By regulating the immune system and reducing inflammation, it can help ease symptoms and improve overall quality of life.
  • chronic pain disorders: Conditions like fibromyalgia and complex regional pain syndrome (CRPS) may benefit from LDN, as it can help reduce pain and enhance daily functioning.
  • inflammatory bowel diseases: LDN has shown potential in managing Crohn’s disease and ulcerative colitis by reducing inflammation in the gut and promoting better digestive health.
  • cancer support: Some individuals use LDN as a complementary therapy alongside conventional cancer treatments. It may boost the immune system and potentially improve outcomes, though further research is needed in this area.
  • neurological disorders: LDN has been explored for conditions like Parkinson’s disease and Alzheimer’s disease, where it may help slow disease progression and alleviate symptoms. However, more studies are required to confirm its effectiveness.
  • irritable bowel syndrome (IBS): LDN can help reduce inflammation in the intestines, relieving symptoms such as abdominal pain, bloating, and irregular bowel movements.

LDN 1mg capsules are generally well-tolerated, but it is crucial to consult a healthcare provider before starting treatment. They can help determine if LDN is appropriate for your specific condition and guide you on proper usage.

How do you use Low Dose Naltrexone (LDN) 4.5mg capsules?

To use Low Dose Naltrexone (LDN) 4.5mg capsules, follow these general guidelines:

  • Dosage: Take one 4.5mg capsule daily, preferably at bedtime. The timing helps to align with the body's natural rhythms and optimise endorphin production.
  • Consistency: Take the capsule at the same time each day to maintain steady levels in the body.
  • With or Without Food: LDN can be taken with or without food, but maintaining a consistent routine can help with adherence.
  • Swallowing: Swallow the capsule whole with water. Do not crush or chew the capsule.
  • Alternative Timing: If taking LDN at night disturbs your sleep, you can switch to taking it in the morning, as advised by your healthcare provider.

Always follow the specific instructions provided by your healthcare provider, who may adjust the dose or timing based on your individual needs and condition.

Who should not use Low Dose Naltrexone (LDN)?

Avoid taking opiates while using low-dose naltrexone 4.5mg capsules. Although this medication generally blocks some of the effects of opiates (such as the euphoric "high"), taking high doses of opiates can still lead to severe breathing difficulties and circulatory problems, which could result in opiate poisoning.

  • Do not use low-dose naltrexone 4.5mg capsules if you are still dependent on opiates, as it can trigger severe withdrawal symptoms.
  • Be sure to inform every healthcare provider that you are using low-dose naltrexone 4.5mg capsules If you require anesthesia in an emergency, non-opiate-based anesthetics should be used. If opiate-containing anesthetics are necessary, higher doses may be required, and you may be more susceptible to side effects such as breathing difficulties and circulatory issues.
  • Do not attempt to counteract the blocking effects of low-dose naltrexone 4.5mg capsules by taking high doses of opiates. There is a risk that opiates could remain in your system after the effects of naltrexone have worn off, potentially leading to an unintentional overdose with serious consequences.
  • Low-dose naltrexone 4.5mg capsules are metabolised by the liver and kidneys. Since liver problems are common in individuals with opiate dependence, your doctor will perform liver function tests before and during treatment.

Other Medicines and Low-Dose Naltrexone 4.5mg capsules:

Inform your doctor if you are taking, have recently taken, or might take any other medications, including those obtained without a prescription. Some common medications contain opiates and may not be effective while you are using low-dose naltrexone 4.5mg capsules.

If you need cough syrups, medications for diarrhea, or pain relievers, inform your doctor, as these may contain opiates. In emergency cases where opioid-containing drugs are required, the necessary dose for pain relief may be higher than usual. Close medical supervision is essential, as respiratory depression and other symptoms may be more intense and prolonged.

Pregnancy and Breastfeeding:

If you are pregnant, breastfeeding, think you may be pregnant or are planning to have a baby, consult your doctor or pharmacist before taking this medication. Low-dose naltrexone 4.5mg capsules should only be used during pregnancy if the potential benefit to the mother outweighs the possible risks. Breastfeeding is not recommended while taking this medication. Always consult your doctor for advice.

Driving and Using Machines:

Low-dose naltrexone 4.5mg capsules may cause drowsiness or reduce alertness. Do not drive or operate machinery if you experience these effects.

What are the side effects of Low Dose Naltrexone (LDN) 4.5mg capsules?

The side effects of Low Dose Naltrexone (LDN) 4.5mg capsules are generally mild but can include:

  • Sleep Disturbances: Some people may experience vivid dreams or insomnia.
  • Digestive Issues: Nausea, constipation, or diarrhea can occur, especially when starting treatment.
  • Fatigue: Feeling unusually tired or drowsy.
  • Headaches: Mild to moderate headaches are possible.
  • Mood Changes: Some individuals may experience mood swings or feelings of euphoria.
  • Joint or Muscle Pain: Achiness or discomfort in muscles or joints.

These side effects are usually temporary and may diminish as the body adjusts to the medication. If side effects persist or worsen, it's important to consult your healthcare provider.

Does Low Dose Naltrexone (LDN) 4.5mg capsules interact with other medicines?

Inform your doctor if you are currently taking, have recently taken, or plan to take any other medications, including those available over the counter. Some common medications contain opiates and may not work effectively while you are using low-dose naltrexone.

If you require cough syrups, diarrhea medications, or pain relievers, let your doctor know, as these might contain opiates. In emergency situations where opioid-containing drugs are necessary, higher doses may be required for effective pain relief. Close medical supervision is crucial, as there is an increased risk of respiratory depression and other prolonged or intensified side effects.

Low Dose Naltrexone (LDN)4.5mg capsules FAQs

What is Low Dose Naltrexone (LDN)?

Low Dose Naltrexone (LDN) is a medication used in small doses (usually between 0.5mg and 4.5mg) to help manage various conditions, including autoimmune diseases, chronic pain, and some neurological conditions. It works by boosting the body's production of endorphins and modulating the immune system.

How does LDN work?

LDN works by temporarily blocking opioid receptors in the brain, which stimulates the production of endorphins, the body's natural painkillers. It also affects immune function by modulating inflammation and regulating immune responses.

What conditions can LDN help treat?

LDN is commonly used to manage conditions such as fibromyalgia, multiple sclerosis, Crohn’s disease, rheumatoid arthritis, lupus, and even certain cancers. It is also used for chronic pain management and as a complementary treatment for conditions related to immune system dysfunction.

How do I take Low Dose Naltrexone (LDN) 4.5mg capsules?

LDN is typically taken once daily, usually at night before bedtime. If sleep disturbances occur, it may be taken in the morning. Always follow your healthcare provider's instructions regarding dosage and timing.

What are the common side effects of LDN?

Some common side effects of LDN may include sleep disturbances (like vivid dreams or insomnia), nausea, digestive issues (constipation or diarrhea), headaches, fatigue, and mild mood changes. These effects usually subside after a few days to weeks.

Can LDN be taken with other medications?

LDN can generally be taken alongside other medications, but it’s important to inform your healthcare provider about any current medications to avoid potential interactions, especially with other immune-modulating drugs or painkillers.

Is LDN safe to use for long-term treatment?

LDN is generally considered safe for long-term use. However, it’s important to regularly check in with your healthcare provider to monitor for any changes in your condition or side effects, particularly when used for managing chronic conditions.

Can I take LDN if I’m pregnant or breastfeeding?

It’s best to avoid using LDN during pregnancy or while breastfeeding unless advised by a healthcare provider. There is limited information on its safety in these situations, so a discussion with a doctor is crucial.

Will LDN cause any withdrawal symptoms?

Since LDN is used at much lower doses than the typical naltrexone treatment for addiction, it is unlikely to cause withdrawal symptoms. However, sudden discontinuation should be done under medical supervision to ensure safety.

How long does it take for LDN to start working?

Some people may experience benefits from LDN within a few days, while for others, it may take several weeks to notice improvements in symptoms. Patience is required, as it can take time for the body to adjust and for the full effects of LDN to become noticeable.

Download patient leaflet

low dose naltrexone 4.5mg capsules medicalmojo.co.uk

Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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