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Mebeverine 135mg Tablets

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Mebeverine is a medication commonly used to treat symptoms of irritable bowel syndrome (IBS) and other related conditions characterized by spasms and involuntary contractions of the gastrointestinal tract. It works as an antispasmodic, helping to relax the intestinal muscles and alleviate discomfort such as cramps, bloating, diarrhea, and constipation. Mebeverine is effective because it directly acts on the smooth muscles of the intestine, stabilizing nerve signals and muscle responses without affecting normal bowel movements. This makes it a preferred choice for many patients seeking relief from IBS symptoms without the side effects associated with other treatments.

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Mebeverine 135mg Tablets
SKU: MEB135 Category: Tags: ,

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1 x 100, 2 x 100

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


What is Mebeverine?

Mebeverine 135 mg film-coated tablets are formulated with the active ingredient mebeverine hydrochloride, which is categorized as an antispasmodic medication. This type of medicine is specifically designed to ease the muscle contractions in the gastrointestinal tract.

Mebeverine functions by relaxing the smooth muscles of the gut, which helps to alleviate symptoms associated with various gastrointestinal disorders. It is primarily used to treat conditions like irritable bowel syndrome (IBS) and is also effective in managing symptoms of other related conditions such as chronic irritable colon, spastic constipation, mucous colitis, and spastic colitis.

The effectiveness of mebeverine makes it a valuable treatment option for patients experiencing discomfort due to these gastrointestinal issues, as it helps to reduce the painful spasms and cramps without influencing the normal rhythm of the bowel. This targeted approach ensures that the gastrointestinal tract functions more smoothly and with less discomfort, improving the quality of life for individuals suffering from these chronic conditions.

What is the active ingredient in Mebeverine?

The active ingredient in each tablet is Mebeverine hydrochloride 135mg.

What is Mebeverine used for?

Irritable bowel syndrome (IBS) is a prevalent condition characterized by spasms and pain in the intestines. The intestines are elongated muscular tubes through which food travels during digestion. When these muscles spasm or contract too tightly, it results in pain. This medicine helps by alleviating these spasms and easing the associated pain and discomfort of IBS.

The primary symptoms of IBS can include:

  • Stomach pain and cramping
  • Persistent diarrhea, or alternating between constipation and diarrhea
  • Bloating and excess gas
  • Passing stools that are small, hard, pellet-like, or ribbon-like

These symptoms can differ widely among individuals. If symptoms persist, worsen, or if new symptoms appear, it is important to consult a doctor. Concerns about symptoms should also be discussed with a healthcare provider.

Managing IBS often involves dietary and lifestyle changes:

  • The impact of IBS can vary, so dietary adjustments should be tailored to how IBS affects you individually. If certain foods exacerbate your symptoms, avoiding these foods may provide relief.
  • Incorporating a high-fiber diet may be beneficial, but it's best to seek advice from a pharmacist or dietitian for tailored dietary guidance.
  • Stress management and relaxation techniques can also be effective in alleviating IBS symptoms. Allocating time each day to relax and de-stress can significantly help manage the condition.

Adopting these strategies in conjunction with medical treatment can provide comprehensive management of IBS and lead to a better quality of life.

How does Mebeverine work?

Mebeverine is an antispasmodic medication, which means it helps to relax the muscles in the digestive tract. It works by targeting the muscle cells in the gut, preventing them from contracting too tightly, which is what usually causes painful spasms and cramps. This action helps to smooth out the muscle movements without interfering with the normal digestion process. Because Mebeverine specifically eases muscle tension without altering the overall function of the digestive system, it effectively reduces discomfort associated with conditions like irritable bowel syndrome (IBS) without causing side effects like constipation or diarrhea. Essentially, Mebeverine helps to ease stomach cramps and discomfort by relaxing the muscles in the gut, making it particularly useful for managing symptoms of IBS and related digestive conditions.

How do you use Mebeverine?

Always follow the instructions provided by your doctor or pharmacist when taking this medicine. If you are unsure about any of the instructions, do not hesitate to ask for clarification. It's best to take the tablet about 20 minutes before a meal since some people experience stronger symptoms after eating. Swallow the tablet whole with water, without chewing it. Dosage for Adults (including the elderly):
  • The usual dosage is one tablet taken three times a day.
  • Do not exceed three tablets in a day.
  • Your doctor may reduce the dosage if your symptoms improve.
Children and Adolescents:
  • Mebeverine is not recommended for individuals under 18 years of age.
If you take more Mebeverine than you should:
  • In case of an overdose, immediately contact your doctor or visit the nearest hospital emergency department. Bring this leaflet and any remaining tablets with you.
If you forget to take Mebeverine:
  • If you miss a dose, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed dose. Never take a double dose to compensate for the missed one.
If you stop taking Mebeverine:
  • Continue taking Mebeverine even if you feel better, unless your doctor advises you to stop. Discontinuing the medication without consulting your doctor could lead to a return of symptoms.
If you have any more questions about using this medicine, consult your doctor or pharmacist for more information.

Who should not use Mebeverine?

Avoid taking Mebeverine if you are allergic to mebeverine or any of the other components listed in the ingredients section of the medication packaging.

Warnings and Precautions:

Before taking Mebeverine, it's important to consult with your doctor or pharmacist if:
  • You notice new symptoms or if your existing symptoms worsen.
  • You have liver or kidney problems.
If any of the above conditions apply to you, or if you are unsure, seek advice from your doctor or pharmacist before starting Mebeverine. Interactions with Other Medicines: While Mebeverine is not known to interact significantly with other medicines, always inform your doctor or pharmacist about any other medications you are currently taking or plan to take. Mebeverine and Alcohol: Alcohol consumption does not affect the action of Mebeverine 135 mg film-coated tablets, so you may drink alcohol while taking this medication. Pregnancy, Breastfeeding, and Fertility: If you are pregnant, breastfeeding, think you might be pregnant, or are planning to become pregnant, consult your doctor for advice before using Mebeverine. There is limited information on the safety of Mebeverine in pregnant women. Your doctor may recommend discontinuing Mebeverine before you conceive or as soon as you find out you are pregnant. Mebeverine is not recommended for use while breastfeeding. Driving and Using Machines: Mebeverine is unlikely to impair your ability to drive or operate machinery. Mebeverine Contains Lactose: If you have been advised by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this medication. Mebeverine Contains Sodium: This medicine contains less than 1 mmol of sodium (23 mg) per film-coated tablet, which means it is essentially sodium-free.

What are the side effects with Mebeverine?

Like all medications, this one may also cause side effects, although not everyone experiences them. If you encounter any of the following severe reactions, stop taking the tablets immediately and seek urgent medical attention from your doctor or the nearest hospital:
  • Difficulty breathing, swelling of the face, neck, lips, tongue, or throat, which are signs of severe allergic reactions.
Other Possible Side Effects: You might also experience other allergic reactions such as:
  • Skin reactions
  • Inflamed or reddened skin
  • Swelling
  • Hives
  • Itching
  • Skin rashes
If you experience any side effects, please inform your doctor or pharmacist. This includes side effects that are not mentioned in the medication leaflet. Reporting Side Effects: Should you notice any side effects, report them to your doctor, pharmacist, or nurse. You also have the option to report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard. Reporting side effects contributes valuable information regarding the safety of this medication.

Does Mebeverine interact with other medicines?

Mebeverine is generally considered to have a low potential for interactions with other medicines. This is because it is not extensively metabolized by the liver and does not have significant effects on liver enzymes that usually metabolize other drugs. Additionally, Mebeverine is not known to significantly affect the absorption, distribution, metabolism, or excretion of other medications.

However, even though interactions are rare, it's always important to inform your doctor or pharmacist about all the medications you are currently taking, including over-the-counter drugs, prescriptions, and herbal supplements. This will help them ensure that Mebeverine is safe to use in conjunction with your other treatments. If you have specific concerns about potential interactions, your healthcare provider can provide the most personalized and accurate advice.

Mebeverine FAQs

What is Mebeverine?

Mebeverine is a medication used to alleviate symptoms of irritable bowel syndrome (IBS) and other similar conditions that cause spasmodic pain in the gut. It contains mebeverine hydrochloride, an antispasmodic agent, which helps to relax the muscles in the gastrointestinal tract. This relaxation helps reduce painful spasms, bloating, diarrhoea, and constipation associated with IBS, allowing individuals to enjoy meals without discomfort. Mebeverine is available by prescription and is typically packaged in boxes of 100 tablets for adults over the age of 18.

How does Mebeverine treat chronic IBS?

IBS often triggers gut and bowel spasms as food passes through, leading to intense pain and discomfort. Mebeverine works by calming these spasms through its antispasmodic properties, directly targeting the smooth muscles in the bowels. This not only relieves the immediate discomfort but also helps manage conditions associated with chronic irritable colon, spastic constipation, mucous colitis, and spastic colitis.

What are the differences between Colofac and Mebeverine?

Colofac is a brand name for mebeverine hydrochloride, while Mebeverine is a generic version. Both medications contain the same active ingredient and offer the same effectiveness. However, Mebeverine is generally less expensive than Colofac, making it a popular choice among patients managing IBS symptoms.

What lifestyle changes can help manage IBS?

Diet and lifestyle adjustments play a crucial role in managing IBS. Avoiding known food triggers and stimulants like caffeine and fizzy drinks can reduce symptoms. Maintaining a high-fiber diet and staying hydrated are also beneficial. Keeping a food diary can help identify what exacerbates your symptoms. Additionally, regular relaxation and stress management can significantly reduce IBS flare-ups.

How should Mebeverine be taken?

The typical dosage for adults and children over 12 is one tablet taken up to three times a day, about 20 minutes before meals. Swallow the tablets whole with water. It's important to start taking Mebeverine when symptoms appear and to stop once they subside, which could be within a couple of weeks. If symptoms persist after two weeks or worsen, discontinue use and consult your doctor.

What are the ingredients in Mebeverine tablets?

The active ingredient in Mebeverine tablets is mebeverine hydrochloride at a strength of 135mg per tablet. Inactive ingredients may include lactose monohydrate, cellulose, microcrystalline, povidone, and others, depending on the manufacturer. It's important to review the patient information leaflet for a complete list of ingredients due to potential variations and allergens.

What are the possible side effects of Mebeverine?

While many people do not experience side effects, some may encounter skin irritations, bloating, dry mouth, or heartburn. Serious allergic reactions like urticaria, angioedema, and face edema can occur. If you experience any severe reactions or if side effects persist, stop taking Mebeverine and consult your doctor.

Are there any warnings associated with Mebeverine?

Mebeverine should not be taken if you are allergic to any of its ingredients. If you have kidney or liver issues, consult your doctor before starting Mebeverine. It is also important to discuss its use if you are pregnant or breastfeeding, as limited safety information is available for these conditions.

For comprehensive guidance on taking Mebeverine and managing its effects, always refer to the detailed patient information leaflet and consult your healthcare provider.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.2315.pdf

Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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