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Dutasteride 0.1% Minoxidil 10% Topical Hair Loss Liquid

from£34.99

The Dutasteride 0.1% Minoxidil 10% hair loss liquid is a potent and advanced treatment formulated to combat hair loss and promote hair regrowth. This dual-action solution combines the efficacy of two clinically proven active ingredients—dutasteride and minoxidil—to provide a comprehensive approach to managing hair loss in men.

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Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid
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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


What is Dutasteride 0.1% Minoxidil 10% hair loss liquid

Dutasteride 0.1% Minoxidil 10% hair loss liquid is used to treat hereditary hair loss in men by preventing further hair loss and aiding hair regrowth. It contains dutasteride and minoxidil and prevents the excess production of dihydrotestosterone (DHT), and improves blood flow to the hair follicles on your scalp.

The Dutasteride 0.1% Minoxidil 10% hair loss liquid is a specialised compounded topical treatment designed to combat hair loss and promote hair regrowth. This solution combines the potent effects of dutasteride a 5-alpha reductase inhibitor that prevents the conversion of testosterone to dihydrotestosterone (DHT), and minoxidil, a vasodilator that enhances blood flow to hair follicles. By reducing DHT levels, dutasteride helps to halt hair thinning and stimulate new hair growth, while minoxidil increases nutrient and oxygen supply to the hair follicles, encouraging thicker, stronger hair.

You may have heard about finasteride and its use in hair loss, so what is dutasteride? Well, dutasteride and finasteride function similarly by inhibiting the enzymes, 5-alpha reductase types 1 and 2, in the male body that produce DHT. Finasteride primarily targets 5-alpha reductase type 2, whereas Dutasteride inhibits both types 1 and 2. Dutasteride is also a more potent inhibitor of these enzymes, resulting in a greater decrease in DHT production and, consequently, reduced hair loss.

Together, these two active ingredients provide a comprehensive approach to managing androgenetic alopecia, making this solution an effective option for both men to improve their hair density and quality.

 

What are the active ingredients in Dutasteride 0.1% Minoxidil 10% hair loss liquid?

Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid contains the active ingredient dutasteride and minoxidil. Dutasteride belongs to a group of medicines known as Type II 5-alpha reductase inhibitors. It is similar to the more famous hair loss product finasteride, but while finasteride blocks only the type 2, 5 -alpha reductase, dutasteride blocks both the type 2 and type 1 5 -alpha reductase. This means you get a much greater suppression of DHT levels with dutasteride. Minoxidil on the other hand, began its pharmaceutical career as an antihypertensive before it transitioned to its use hair loss. It abilility to cause vasodilation was able to stimulate hair growth in addition to reducing blood pressure.  

What is Dutasteride 0.1% Minoxidil 10% hair loss liquid used for?

Dutasteride 0.1% Minoxidil 10'% hair loss liquid is used to help prevent further hair loss in male pattern balding whilst also stimulating hair growth. Dutasteride 0.1% Minoxidil 10% hair loss liquid is used to treat hereditary hair loss in men by preventing further hair loss and aiding hair regrowth. It contains dutasteride and minoxidil and prevents the excess production of dihydrotestosterone (DHT), and improves blood flow to the hair follicles on your scalp. Dutasteride works by lowering the levels of DHT in the scalp. This reduction helps to reverse the balding process, promoting increased hair growth and preventing further hair loss. Dutasteride 0.1% Minoxidil 10% hair loss liquid contains the active ingredient dutasteride, which belongs to a group of medicines known as 5 alpha reductase inhibitors. Unlike finasteride, which is only able to inhibit type 2 5-alpha reductase, dutasteride is able to inhibit both the type 1 and 2 5-alpha reductase. It is intended for use in men only. Dutasteride is prescribed for the treatment of male pattern hair loss, also known as androgenetic alopecia. It helps to prevent further hair loss while the minoxidil encourages blood flow to the scalp helping new hairs to grow. Men with mild to moderate hair loss can benefit from using dutasteride.
  • It works best in men with hair loss or thinning at the top of the scalp.
  • Younger men, those who have been losing hair for a short period, or those with a small area of baldness are likely to experience the best results.
  • Dutasteride0.1% Minoxidil 10% hair loss liquid is unlikely to benefit men who have been bald for many years or have a large area of hair loss.
Hereditary hair loss is recognisable by:
  • The pattern of hair loss (see diagrams below)
  • Gradual onset and progression
  • Family history of hair loss
  • No other symptoms are present with your hair loss
How Does Hair Grow? Your hair grows about 1 centimetre (half an inch) each month. Hair grows from hair follicles located under your skin. A single scalp hair grows continuously for 2-4 years (growth phase) and then stops growing for 2-4 months (rest phase). After this, the hair falls out, and new, healthy hair begins to grow, repeating the cycle. The hairs on your scalp are always at different stages of this cycle, so it is normal to lose some scalp hair every day. What Is Male Pattern Hair Loss? Male-pattern hair loss is a common condition in which men experience thinning hair on the scalp, often leading to a receding hairline and/or balding on the top of the head. This condition is believed to result from a combination of genetic factors and the hormone dihydrotestosterone (DHT). DHT shortens the growth phase of hair and causes it to thin, leading to male-pattern hair loss. These changes can begin in some men as early as their 20s and tend to become more prevalent with age. Prolonged hair loss over time may result in permanent hair loss.
Male pattern baldness stages Medicalmojo.co.uk
Male pattern baldness stages Medicalmojo.co.uk

How does Dutasteride 0.1% Minoxidil 10% Hair Loss solution work?

The Dutasteride 0.1% Minoxidil 10% hair loss liquid works through a synergistic mechanism of action that targets both the hormonal and vascular causes of hair loss. Dutasteride, a 5-alpha reductase inhibitor which targets both isotypes, 1 and 2, plays a crucial role by preventing the conversion of testosterone into dihydrotestosterone (DHT). DHT is a hormone that contributes to hair follicle miniaturisation and hair loss in androgenetic alopecia. By lowering DHT levels in the scalp, dutasteride helps to halt the progression of hair thinning and promotes the regrowth of stronger, healthier hair. Minoxidil, a vasodilator, enhances blood circulation to the hair follicles by widening the blood vessels. This increased blood flow delivers more oxygen and essential nutrients to the follicles, thereby stimulating hair growth and improving hair density. The 10% concentration of minoxidil in the solution maximises its efficacy, encouraging the growth of thicker and more resilient hair. Together, these two active ingredients, duasteride and minoxidl, offer a comprehensive and effective treatment for hair loss, addressing both the underlying hormonal imbalances and the need for enhanced follicular nutrition.
How do you use Dutasteride 0.1% Minoxidil 10% hair loss solution?
  1. Preparation:
  • Ensure your scalp and hair are clean and dry before applying the solution. • Wash your hands thoroughly before and after application.
  1. Application:
  • Apply the recommended dose (as prescribed by your doctor) directly to the affected areas of the scalp. The usual dose is 1ml or six sprays. • Gently massage the solution into the scalp using your fingertips to ensure even distribution. • Avoid contact with your eyes, mouth, and other mucous membranes. If contact occurs, rinse thoroughly with water.
  1. Frequency:
  • Apply the solution once daily as directed by your healthcare provider. • It is important to use the solution consistently for the best results.

Who should not use the Dutasteride 0.1% Minoxidil 10% hair loss solution?

Do Not Take Dutasteride If:
  • You are allergic to dutasteride, other 5-alpha reductase inhibitors, or any of the ingredients in this medicine.
  • You have severe liver disease.
If any of these conditions apply to you, do not take this medicine until you have consulted with your doctor. This medicine is for men only and must not be taken by women, children, or adolescents.

Warnings and Precautions

Consult your doctor or pharmacist before taking Dutasteride:
  • Inform your doctor if you have liver problems. If you have a history of liver disease, additional check-ups may be required while taking Dutasteride.
  • Women, children, and adolescents should not handle leaking Dutasteride 0.1% Minoxidil 10% hair loss liquid, as the active ingredient can be absorbed through the skin. If contact occurs, wash the area immediately with soap and water.
  • Use a condom during sexual intercourse. Dutasteride 0.1% Minoxdil 10% hair loss liquid can be present in semen and may affect the normal development of a male baby if your partner is pregnant or may become pregnant.
  • Dutasteride has been shown to decrease sperm count, semen volume, and sperm motility, potentially reducing fertility.
  • Dutasteride can affect PSA (prostate-specific antigen) blood tests used to detect prostate cancer. Inform your doctor that you are taking dutasteride if you are undergoing a PSA test. Regular PSA testing is recommended for men taking dutasteride.
  • In clinical studies, men at increased risk of prostate cancer who took dutasteride experienced a serious form of prostate cancer more often than those who did not take dutasteride. The impact of dutasteride on this serious form of cancer is not clear.
  • Dutasteride may cause breast enlargement and tenderness. If you experience these symptoms, or if you notice breast lumps or nipple discharge, contact your doctor as these may indicate a serious condition such as breast cancer.

Food and Drink

Dutasteride can be taken with or without food.

Pregnancy, Breast-Feeding, and Fertility

If your partner is pregnant, breast-feeding, or planning to become pregnant, consult your doctor or pharmacist before taking this medicine. Pregnant women must not handle leaking Dutasteride 0.1% Minoxidil 10% hair loss liquid, as the active ingredient can be absorbed through the skin and affect the development of a male baby, especially in the first 16 weeks of pregnancy. Use a condom during sexual intercourse to avoid exposing your partner to dutasteride through semen. Dutasteride has been shown to reduce sperm count, semen volume, and sperm movement, which may reduce male fertility. Talk to your doctor or pharmacist before taking Dutasteride 0.1% Minoxidil 10% hair loss liquid if:
  • You are going to have a blood test for prostate cancer called PSA (prostate-specific antigen), as Dutasteride can affect the results of this test.
  • You have breast cancer.
Mood Alterations and Depression Mood changes such as depressed mood, depression, and, less frequently, suicidal thoughts have been reported in patients treated with dutasteride. If you experience any of these symptoms, stop taking Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid and contact your doctor immediately for further advice. Children and Adolescents Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid should not be used in children. Pregnancy, Breast-Feeding, and Fertility
  • Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid is intended for the treatment of male pattern hair loss in men only.
  • Dutasteride should not be taken by women.
  • This product is for men only and should NOT be used by women, especially if pregnant or breastfeeding.
  • Do not touch the Dutasteride 0.1% Minoxidil 10% solution if you are a woman who is pregnant or planning to become pregnant.
  • If a pregnant woman comes into contact with the Dutasteride 0.1% Minoxidil 10% hair loss solution, she should speak to a doctor.
Consult your doctor or pharmacist if:
  • You are unsure whether your scalp is normal and healthy.
  • You suffer from heart disease, abnormal heart rhythms, chest pains, or circulation disorders.#
  • You are taking or using other medicines, especially certain blood pressure medicines called 'vasodilators', e.g., hydralazine, as minoxidil may interact with these medications.
Driving and Using Machines Dutasteride is not likely to affect your ability to drive, use tools, or operate machines. However, minoxidil may cause dizziness or low blood pressure. If you experience these side effects, do not drive or operate machinery.    

What are the side effects with Dutasteride 0.1% Minoxidil 10% hair loss solution?

This medicine can cause side effects like all medications, although not everyone experiences them. Some side effects may be temporary and improve with continued treatment or upon stopping the medication. Signs of an allergic reaction can include:
  • Itchy skin rash
  • Hives (similar to nettle rash)
  • Swelling of the eyelids, face, lips, arms, or legs
If you experience any of these symptoms, stop using Dutasteride 0.1% Minoxdil 10% hair loss liquid and contact your doctor immediately.

Serious Side Effects

  • Stop taking the Dutasteride 0.1% Minoxidil 10% hair loss liquid and seek immediate medical attention if you experience any of the following:
  • Allergic Reaction: Symptoms such as swelling of the lips, face, tongue, or throat; difficulty swallowing; hives (lumps under the skin); and breathing difficulties.
  • Depression: Feelings of severe sadness and worthlessness.
  • Breast Changes: Any changes in breast tissue, such as lumps, pain, enlargement, or nipple discharge, as these may indicate a serious condition like breast cancer.
  • Chest pain
Stop using and consult your doctor if you experience:
  • Low blood pressure, fast heartbeat, palpitations.
  • Faintness or dizziness, swollen hands or feet, shortness of breath.
  • Sudden unexplained weight gain, persistent local redness or rash.

Common Side Effects (May Affect Up to 1 in 10 Men)

  • Impotence or erectile dysfunction (difficulty achieving or maintaining an erection), which may persist after stopping Dutasteride 0.1% Minoxdil 10% hair loss liquid.
  • Decreased sex drive (libido), which may persist after stopping Dutasteride 0.1% Minoxidil 10% hair loss liquid.
  • Ejaculation issues, such as reduced semen volume during sex, which may persist after stopping Dutasteride 0.1% Minoxidil 10% hair loss liquid.
  • Breast enlargement or tenderness (gynecomastia)
  • Dizziness when taken with tamsulosin

Uncommon Side Effects (May Affect Up to 1 in 100 Men)

  • Heart failure (reduced efficiency in pumping blood, symptoms may include shortness of breath, extreme fatigue, and swelling in the ankles and legs)
  • Hair loss (typically from the body) or unusual hair growth
  • Nausea

Unknown Frequency (Cannot Be Estimated from Available Data)

  • Depression
  • Pain and swelling in the testicles

Frequency Not Known

  • Breast swelling or tenderness
  • Testicular pain
  • Blood in semen
  • Palpitations (feeling your heartbeat)
  • Persistent difficulty in maintaining an erection after discontinuation of treatment
  • Persistent decrease in sex drive after discontinuation of treatment
  • Persistent problems with ejaculation after discontinuation of treatment
  • Male infertility and/or poor quality of semen
  • Changes in liver function, detectable by blood tests
  • Anxiety
  • Suicidal thoughts

Rare side-effects:

Change in hair texture.

Other possible side-effects:

Depressed mood, eye irritation, vomiting, scalp irritation, acne-like rash, temporary hair loss, and change in hair colour. If any of these side effects become serious, or if you notice any side effects not listed above or in the product information  leaflet, please inform your doctor or pharmacist. Keeping a note of what happened, when it started, and how long it lasted can be helpful.

Reporting of Side Effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. Reporting side effects can help provide more information on the safety of this medicine.  

Does the Dutasteride 0.1% Minoxidil 10% hair loss solution interact with any other medicines?

When using the Dutasteride 0.1% Minoxidil 10% Hair Loss Solution, it's important to be aware of potential drug interactions that may affect the efficacy or safety of the treatment. Here are some key points to consider: Oral Finasteride or dutasteride: If you are already taking oral dutasteride or finasteride for hair loss or benign prostatic hyperplasia (BPH), using a topical solution containing dutasteride might increase the risk of systemic side effects, including decreased libido, erectile dysfunction, and other hormonal imbalances. It is essential to inform your healthcare provider if you are using both forms of finasteride. Antihypertensive Medications: Minoxidil is a vasodilator and can lower blood pressure. If you are taking antihypertensive medications (blood pressure-lowering drugs), using a minoxidil-containing solution may enhance the blood pressure-lowering effects, potentially leading to hypotension (abnormally low blood pressure). Regular monitoring of blood pressure is recommended. Topical Corticosteroids or Other Dermatological Treatments: The concurrent use of other topical medications, especially corticosteroids, retinoids, or other dermatological treatments on the scalp, may increase the risk of skin irritation or alter the absorption of minoxidil and finasteride. Consult your healthcare provider before combining these treatments. Oral Minoxidil: If you are taking oral minoxidil for severe hypertension, adding a topical minoxidil solution may increase the risk of systemic side effects such as tachycardia (rapid heart rate) and fluid retention. Ensure your healthcare provider is aware of all forms of minoxidil you are using. Other Hair Loss Treatments: Combining dutasteride and minoxidil with other hair loss treatments like dutasteride, spironolactone, or hair growth supplements may lead to compounded effects or unexpected interactions. Always discuss with your healthcare provider before starting any additional treatments. Anticoagulants and Antiplatelet Drugs: While there are no specific known interactions, patients using anticoagulants (blood thinners) or antiplatelet drugs should be cautious as minoxidil's vasodilatory effects might theoretically impact clotting. Close monitoring and consultation with a healthcare provider are advised. It's crucial to discuss all current medications, supplements, and medical conditions with your healthcare provider before starting the Dutasteride 0.1% Minoxidil 10% hair loss liquid to avoid potential interactions and ensure safe and effective use of the product. Inform your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.  
FAQs What is Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid? This is a topical treatment combining dutasteride and minoxidil to help combat hair loss and promote hair regrowth in men and women. How does Dutasteride 0.1% Minoxidil 10% Hair Loss Solution work? Dutasteride reduces DHT levels, preventing hair follicle miniaturisation, while minoxidil increases blood flow to hair follicles, stimulating growth and improving hair density. How should I apply Dutasteride 0.1% Minoxidil 10% Hair Loss Solution? Apply 1 ml or six sprays of the solution directly to the affected areas of the scalp once daily, ideally in the morning and evening. Ensure your scalp is clean and dry before application. What are the possible side effects of using this hair loss solution? Common side effects include scalp irritation, redness, and itching. Systemic side effects may include decreased libido and dizziness. Consult your healthcare provider if you experience severe or persistent side effects. Can women use Dutasteride 0.1% Minoxidil 10% Hair Loss Solution?
  • Dutasteride 0.1% Minoxidil 10% Hair Loss Liquid is intended for the treatment of male pattern hair loss in men only.
  • Dutasteride should not be taken by women.
  • This product is for men only and should NOT be used by women, especially if pregnant or breastfeeding.
  • Do not touch the Dutasteride 0.1% Minoxidil 10% solution if you are a woman who is pregnant or planning to become pregnant.
  • If a pregnant woman comes into contact with the Dutasteride 0.1% Minoxidil 10% hair loss solution, she should speak to a doctor.
How long does it take to see results with this hair loss solution? Initial results can be seen as early as 3 to 4 months with consistent use, but it may take up to 6 to 12 months to see significant improvements. Can I use other hair products while using Dutasteride 0.1% Minoxidil 10% Hair Loss Solution? Yes, you can use other hair products, but apply them after the solution has dried completely. Avoid using other topical treatments on the scalp unless advised by your healthcare provider. What should I do if I miss a dose? If you miss a dose, apply it as soon as you remember. If it’s almost time for your next dose, skip the missed dose and resume your regular schedule. Do not double the dose to make up for the missed one. Are there any interactions with other medications? Yes, potential interactions include antihypertensive medications, other hair loss treatments, and topical corticosteroids. Consult your healthcare provider about all medications and supplements you are taking. How should I store Dutasteride 0.1% Minoxidil 10% Hair Loss Solution? Store the solution at room temperature, away from direct light and heat. Keep it tightly closed when not in use and out of reach of children.    

Download patient leaflet

Dutasteride 0.1% Minoxidl 10% topical hair loss liquid medicalmojo.co.uk

Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

GP, Medical coach


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Superintendant Pharmacist, Independent Prescriber


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