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Dutasteride 0.5mg capsules

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Dutasteride 0.5mg capsules are a highly effective oral medication designed to address male pattern hair loss (androgenetic alopecia). This condition, characterized by hair thinning and baldness on the top of the head and mid-scalp area, affects a significant number of men. Dutasteride works by targeting the hormonal pathway responsible for hair loss, offering a robust solution for those looking to combat this common issue.

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Dutasteride 0.5mg capsules
SKU: DUT05 Category: Tags: , ,

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1 x 30, 2 x 30, 3 x 30, 4 x 30, 5 x 30

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Overview

Active ingredients

What is it for?

How does it work?

How do you use it?

Warnings and precautions

Side effects

Drug interactions

FAQs

Download patent leaflet

Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Independent prescriber, Superintendent pharmacist.


Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

Medical coaching


What is Dutasteride 0.5?

Dutasteride is an active ingredient in an oral medication that effectively treats genetic male pattern hair loss, specifically targeting the top of the head and mid-scalp area.

Originally developed to treat symptomatic benign prostatic hyperplasia (BPH) in men, dutasteride is chemically similar to finasteride, the active compound in Propecia. Clinical trials have shown dutasteride to be effective in treating both male pattern hair loss and BPH, similar to Propecia.

What is the active ingredient in Dutasteride 0.5mg?

The active ingredient is Dutasteride 0.5mg which is a powerful inhibitor of the 5-alpha reductase enzyme.  

What is Dutasteride 0.5mg used for?

Dutasteride 0.5mg is typically prescribed to treat an enlarged prostate. However, it works similarly to finasteride (Propecia) but is much more potent. This makes dutasteride 0.5mg an alternative option for men looking to retain their hair. Dutasteride 0.5mg contains the active ingredient dutasteride, which inhibits the production of dihydrotestosterone (DHT)—the hormone responsible for hair loss and male pattern baldness. As this medication was not originally designed for hair loss treatment, it is prescribed 'off-label' for this purpose. 'Off-label' means using a medication to treat a condition other than the one it was initially approved for. Despite this, extensive scientific and medical data support the safe use of dutasteride for hair loss. Dutasteride 0.5mg can effectively treat genetic male pattern hair loss, especially on the top of the head and mid-scalp area.
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How does Dutasteride 0.5mg work?

Male pattern baldness (hair loss) is caused by a combination of genetic factors and the male hormone DHT (dihydrotestosterone). Inhibiting the production of DHT reduces hair loss and promotes the growth of thicker hair. Dutasteride and Propecia work similarly by blocking the enzymes in the male body, 5-alpha reductase types 1 and 2, which produce DHT. Propecia primarily inhibits 5-alpha reductase type 2, while Dutasteride inhibits both types. Dutasteride also blocks these enzymes more potently, leading to a greater reduction in DHT production and, consequently, less hair loss.

How to take Dutasteride 0.5mg?

Always take this medication exactly as directed by your doctor or pharmacist. Inconsistent use may affect the monitoring of your PSA levels. If you have any questions, consult your healthcare provider. Dosage Instructions:
  • Recommended Dose: Take one capsule (0.5 mg) daily. Swallow the capsule whole with water. Do not chew or break open the capsule, as contact with the contents may cause irritation to your mouth or throat.
  • Long-Term Treatment: Dutasteride is intended for long-term use. Some men may notice an early improvement in their symptoms, while others may need to take Dutasteride for six months or more before observing any effects. Continue taking Dutasteride as long as your doctor advises.
If You Take More Dutasteride Than Prescribed:
  • Contact your doctor or pharmacist immediately for advice if you accidentally take too many capsules.
If You Forget to Take a Dose:
  • Do not take a double dose to compensate for a missed one. Simply take your next dose at the usual time.
If You Stop Taking Dutasteride:
  • Do not discontinue Dutasteride without consulting your doctor. It may take six months or longer to notice its effects. If you have any further questions about using this medication, ask your doctor or pharmacist.

Who should not take Dutasteride 0.5mg?

Do Not Take Dutasteride If:

  • You are allergic to dutasteride, other 5-alpha reductase inhibitors, or any of the ingredients in this medicine.
  • You have severe liver disease.
If any of these conditions apply to you, do not take this medicine until you have consulted with your doctor. This medicine is for men only and must not be taken by women, children, or adolescents.

Warnings and Precautions

Consult your doctor or pharmacist before taking Dutasteride:
  • Inform your doctor if you have liver problems. If you have a history of liver disease, additional check-ups may be required while taking Dutasteride.
  • Women, children, and adolescents should not handle leaking Dutasteride capsules, as the active ingredient can be absorbed through the skin. If contact occurs, wash the area immediately with soap and water.
  • Use a condom during sexual intercourse. Dutasteride can be present in semen and may affect the normal development of a male baby if your partner is pregnant or may become pregnant.
  • Dutasteride has been shown to decrease sperm count, semen volume, and sperm motility, potentially reducing fertility.
  • Dutasteride can affect PSA (prostate-specific antigen) blood tests used to detect prostate cancer. Inform your doctor that you are taking Dutasteride if you are undergoing a PSA test. Regular PSA testing is recommended for men taking Dutasteride.
  • In clinical studies, men at increased risk of prostate cancer who took Dutasteride experienced a serious form of prostate cancer more often than those who did not take Dutasteride. The impact of Dutasteride on this serious form of cancer is not clear.
  • Dutasteride may cause breast enlargement and tenderness. If you experience these symptoms, or if you notice breast lumps or nipple discharge, contact your doctor as these may indicate a serious condition such as breast cancer.

Food and Drink

Dutasteride can be taken with or without food.

Pregnancy, Breast-Feeding, and Fertility

If your partner is pregnant, breast-feeding, or planning to become pregnant, consult your doctor or pharmacist before taking this medicine. Pregnant women must not handle leaking Dutasteride capsules, as the active ingredient can be absorbed through the skin and affect the development of a male baby, especially in the first 16 weeks of pregnancy. Use a condom during sexual intercourse to avoid exposing your partner to Dutasteride through semen. Dutasteride has been shown to reduce sperm count, semen volume, and sperm movement, which may reduce male fertility.

What are the side effects of Dutasteride 0.5mg?

Like all medications, Dutasteride can cause side effects, although not everyone will experience them.

Allergic Reactions

Signs of an allergic reaction can include:
  • Itchy skin rash
  • Hives (similar to nettle rash)
  • Swelling of the eyelids, face, lips, arms, or legs
If you experience any of these symptoms, stop using Dutasteride and contact your doctor immediately.

Common Side Effects (May Affect Up to 1 in 10 Men)

  • Impotence (difficulty achieving or maintaining an erection), which may persist after stopping Dutasteride
  • Decreased sex drive (libido), which may persist after stopping Dutasteride
  • Ejaculation issues, such as reduced semen volume during sex, which may persist after stopping Dutasteride
  • Breast enlargement or tenderness (gynecomastia)
  • Dizziness when taken with tamsulosin

Uncommon Side Effects (May Affect Up to 1 in 100 Men)

  • Heart failure (reduced efficiency in pumping blood, symptoms may include shortness of breath, extreme fatigue, and swelling in the ankles and legs)
  • Hair loss (typically from the body) or unusual hair growth

Unknown Frequency (Cannot Be Estimated from Available Data)

  • Depression
  • Pain and swelling in the testicles

Reporting of Side Effects

If you experience any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. You can also report side effects directly through the national reporting system, the Yellow Card Scheme. Visit www.mhra.gov.uk/yellowcard or search for "MHRA Yellow Card" in the Google Play or Apple App Store. Reporting side effects helps provide more information on the safety of this medicine.

Does Dutasteride 0.5mg interact with other medicines?

Inform your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. Some medications can interact with Dutasteride, increasing the likelihood of side effects. These include:
  • Verapamil or diltiazem (for high blood pressure)
  • Ritonavir or indinavir (for HIV)
  • Itraconazole or ketoconazole (for fungal infections)
  • Nefazodone (an antidepressant)
  • Alpha-blockers (for enlarged prostate or high blood pressure)
Your doctor may need to adjust your dose of Dutasteride if you are taking any of these medicines.

Dutasteride 0.5mg FAQs

How Long Does Dutasteride Hair Loss Treatment Take to Work?

Improvement in symptoms of male pattern hair loss is typically seen within a few months of starting treatment; however, results may vary from person to person. Similar to Finasteride, it may take one year or more of consistent use before you begin to notice any significant hair regrowth. While dealing with male pattern baldness can be distressing, it’s crucial to remember that treating hair loss is a gradual process, and results won’t occur overnight. During the initial period, you may continue to experience hair loss while taking Dutasteride. However, over time, the medication will start to work in your body, eventually slowing down and even reversing hair loss for some individuals.

Will Dutasteride Regrow Hair?

Dutasteride has been scientifically shown to treat male pattern baldness by blocking the production of the male hormone DHT. By inhibiting this hormone, Dutasteride reduces the rate of hair loss and promotes the growth of thicker, healthier hair. While Dutasteride is highly effective at preventing further hair loss, it cannot repair dead hair follicles. This is why starting treatment as soon as you notice thinning or shedding is recommended. For those already in the advanced stages of male pattern baldness, Dutasteride can still help, but it’s important to manage expectations.

Dutasteride vs. Avodart vs. Propecia

In head-to-head studies, Dutasteride has been found to be more effective than Finasteride. Participants at the end of these studies exhibited more hair growth and less overall hair loss. Avodart and Propecia are the branded versions of the generic medications Dutasteride and Finasteride, respectively. Generic medications are manufactured to the same rigorous standards as their branded counterparts but offer a more cost-effective alternative.

Dutasteride and Erectile Dysfunction

Erectile dysfunction (ED) can occur as a side effect of using oral hair loss treatments like Dutasteride. This may result in the inability to achieve or maintain an erection during the course of treatment, and this side effect may persist after stopping Dutasteride, as it remains in your system for up to 6 months. ED affects up to 1 in 10 men using Dutasteride, meaning most users will not experience this issue. Fortunately, if ED does affect you, there are various treatments available to manage and improve these symptoms.

What is Dutasteride 0.5mg used for?

Dutasteride 0.5mg is primarily used to treat benign prostatic hyperplasia (BPH) in men. It can also be prescribed off-label for male pattern hair loss.

How does Dutasteride work?

Dutasteride works by inhibiting the enzyme 5-alpha reductase, which converts testosterone into dihydrotestosterone (DHT). Reducing DHT levels helps shrink an enlarged prostate and can prevent hair loss.

How long does it take for Dutasteride to show results?

It may take 3 to 6 months to see significant results in reducing prostate size or improving hair growth. Consistent use as prescribed is necessary for effectiveness.

Can women take Dutasteride 0.5mg?

No, Dutasteride is not recommended for women, particularly those who are pregnant or may become pregnant, as it can cause harm to a developing male fetus.

Are there any common side effects of Dutasteride?

Common side effects include impotence, decreased libido, ejaculation issues, and breast tenderness or enlargement. These may persist even after stopping the medication.

Can I take Dutasteride with other medications?

Dutasteride can interact with certain medications, including verapamil, diltiazem, ritonavir, indinavir, itraconazole, ketoconazole, nefazodone, and alpha-blockers. Always inform your doctor of all medications you are taking.

What should I do if I miss a dose of Dutasteride?

If you miss a dose, take it as soon as you remember. If it’s almost time for your next dose, skip the missed dose. Do not take a double dose to make up for a missed one.

Can Dutasteride affect PSA test results?

Yes, Dutasteride can lower PSA levels, which may affect the interpretation of PSA tests used to detect prostate cancer. Inform your doctor that you are taking Dutasteride if you undergo PSA testing.

Is it safe to handle Dutasteride capsules?

Women who are pregnant or may become pregnant should not handle leaking Dutasteride capsules as the active ingredient can be absorbed through the skin and may harm a male fetus.

Can Dutasteride be used to treat hair loss?

Yes, Dutasteride is sometimes prescribed off-label to treat male pattern hair loss. It works by reducing DHT levels, which can help prevent hair loss and promote hair regrowth. If you have any further questions or concerns about Dutasteride 0.5mg, please consult your doctor or pharmacist.

Download patient leaflet

https://www.medicines.org.uk/emc/files/pil.9277.pdf

Checked By
Dr Sarah Thornton
MbChB, Coaching Academy diploma with distinction

Medical coaching


Written By
Shazlee Ahsan
BSc Pharmacy, Independent Prescriber, PgDip Endocrinology, MSc Endocrinology, PgDip Infectious Diseases

Independent prescriber, Superintendent pharmacist.


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