What is Vydura?

Welcome to our latest blog post titled, What is Vydura? This discussion is crucial for those among you who are on a seemingly endless quest to find relief from chronic migraines. If you’ve tried various treatments with little to no success, this post aims to shed light on a potential new solution. Today, we will answer the key question: What is Vydura? We’ll explore how Vydura could be different from other migraine treatments you’ve tried and discuss whether it could be the solution you’ve been searching for. Join us as we delve deep into the details of what Vydura is and how it might help you manage your migraine symptoms more effectively.

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Vydura: The new migraine medication revolutionising treatment

Migraines affect millions of people worldwide, causing debilitating pain and impacting quality of life. Fortunately, innovative treatments are continually being developed to offer relief to sufferers. One such breakthrough is Vydura (rimegepant), a new migraine medication that has been approved for use in the UK. This blog will explore what is Vydura, how it works, and everything you need to know about using it. If you’re seeking treatment for migraines, you can purchase Vydura safely through Medical Mojo after completing a health questionnaire.

What is Vydura?

Vydura, known generically as rimegepant, is a calcitonin gene-related peptide (CGRP) receptor antagonist. It is the first medication in its class to be available as a dissolvable tablet, offering a convenient alternative for migraine sufferers. Approved by the National Institute for Health and Care Excellence (NICE) for both acute and preventive treatment, Vydura provides a new option for those who have found traditional treatments ineffective or unsuitable.

Unlike over-the-counter painkillers or triptans, Vydura targets the underlying processes that cause migraines. It can be used to:

• Treat acute migraine attacks.
• Prevent episodic migraines.

For more details on migraine treatments, visit our blog: Can you take Naproxen for migraines?

How does Vydura Work?

Vydura works by blocking CGRP receptors in the brain. CGRP is a neuropeptide that plays a key role in triggering and sustaining migraines. During a migraine attack, CGRP levels rise, leading to inflammation and pain. By antagonising these receptors, Vydura effectively reduces the frequency and severity of migraine symptoms.

This innovative mechanism sets Vydura apart from traditional migraine treatments, such as triptans, which constrict blood vessels. As a result, Vydura is suitable for individuals who cannot tolerate triptans due to cardiovascular concerns.

History and development of Vydura

Vydura’s journey began with research into the role of CGRP in migraine pathophysiology. After years of clinical trials, Rimegepant was developed and approved for use in the US in 2020 under the brand name Nurtec ODT. NICE approved Vydura for use in the UK in 2023 for both acute and preventive treatment of migraines.

This approval marks a significant milestone in migraine management, offering hope to individuals who struggle with frequent or severe migraines.

Who should not take Vydura?

While Vydura is effective for many, it’s not suitable for everyone. You should not take Vydura if you:

• Are allergic to rimegepant or any of its ingredients.
• Have severe liver or kidney disease.
• Are pregnant or breastfeeding (unless advised by a healthcare professional).
• <18 years of age unless under the care of your doctor.
• Undiagnosed migraine by a healthcare professional.

Always consult your doctor before starting a new medication, especially if you are taking other drugs or have underlying health conditions.

How to take Vydura

Vydura comes in the form of an orodispersible tablet that dissolves quickly on the tongue without the need for water. This makes it convenient for use, even during a migraine attack. Follow these guidelines when taking Vydura:

1. Take one 75 mg tablet as soon as you notice migraine symptoms.
2. Do not take more than one tablet in 24 hours.
3. For preventive use, your doctor may recommend a specific schedule (e.g., every other day).

Consistency is key for preventive treatment, so follow your healthcare provider’s instructions closely.

What are the side effects of Vydura

Like all medications, Vydura may cause side effects, although not everyone experiences them. Common side effects include:

• Nausea
• Fatigue
• Dry mouth

Rare but serious side effects may include allergic reactions such as rash, swelling, or difficulty breathing. If you experience any severe symptoms, seek medical attention immediately.

For a full list of potential side effects, consult the patient information leaflet or speak to your healthcare provider.

Where to buy Vydura in the UK

In the UK, Vydura is available by prescription. You can purchase it conveniently through Medical Mojo, a trusted online pharmacy. To buy Vydura:

1. Complete a health questionnaire on our website.
2. A qualified healthcare professional will review your information.
3. Once approved, your prescription will be dispensed and delivered discreetly to your door.

FAQs about Vydura

1. What makes Vydura different from other migraine treatments?

Vydura is a CGRP receptor antagonist, targeting the root causes of migraines rather than just relieving symptoms. Its dissolvable tablet form also makes it more convenient to use.

2. Can I use Vydura for both prevention and treatment?

Yes, Vydura is approved for both acute treatment and preventive use. Your doctor will determine the best regimen for you.

3. How quickly does Vydura work?

Most users experience relief within two hours of taking Vydura.

4. Is Vydura safe for long-term use?

Clinical trials have shown that Vydura is safe for long-term use when taken as prescribed. However, regular monitoring by your doctor is recommended.

5. Can I take Vydura with other migraine medications?

You should consult your healthcare provider before combining Vydura with other treatments to avoid potential interactions.

Conclusion

Vydura represents a significant advancement in migraine treatment, offering both acute relief and preventive benefits. Whether you struggle with occasional or frequent migraines, this medication could be a game-changer for your quality of life. If you’re considering Vydura, visit Medical Mojo to complete a health questionnaire and begin your journey toward effective migraine management.

For more information on managing migraines and alternative treatments, explore our other blogs: Can You Take Naproxen for Migraines?.

Note: This information is for educational purposes only and should not substitute for professional medical advice.

References

1. Blair, H.A. Rimegepant: A Review in the Acute Treatment and Preventive Treatment of Migraine. CNS Drugs 37, 255–265 (2023). https://doi.org/10.1007/s40263-023-00988-8
2. de Vries, T., Villalón, C.M. and MaassenVanDenBrink, A., 2020. Pharmacological treatment of migraine: CGRP and 5-HT beyond the triptans. Pharmacology & Therapeutics, 211, p.107528.
3. Edvinsson L. Rimegepant oral disintegrating tablet for migraine. Lancet. 2019;394(10200):711–2.
4. European Medicines Agency. VYDURA 75 mg oral lyophilisate: EU summary of product characteristics. 2022. https://www.ema.europa.eu/en/medicines/human/EPAR/vydura.
5. Migraine Trust, no date. NICE approves Rimegepant for acute use on the NHS in England. Available at: https://migrainetrust.org/news/nice-approves-rimegepant-for-acute-use-on-the-nhs-in-england/#:~:text=NICE%20approves%20Rimegepant%20for%20acute%20use%20on%20the%20NHS%20in%20England,-Rimegepant%20is%20now&text=Today%20it%20has%20been%20announced,preventive%20use%20in%20May%202023